By Dr. Noel Menezes
M.D
Associate Professor
Department of Biochemistry
Goa Medical College
Uric acid is a normal body waste product produced by the breakdown of purines. Purines are nitrogen-containing compounds found in the cells of the body, including our DNA. They are also found in many foods such as liver, shellfish, and alcoholic drinks, primarily beer.
When purines are broken down to Uric acid in the blood, the body gets rid of it when you urinate. But if your body makes too much Uric acid, or if your kidneys aren’t working well, Uric acid can build up in the blood. Uric acid levels can also increase when you eat too many high-purine foods or take medicines like diuretics, aspirin, and niacin. Then crystals of Uric acid can form and collect in the joints. This causes painful inflammation leading to a condition called “Gout” which is characterized by inflammation of the joints due to the formation of Uric acid crystals (tophi) in the joints (synovial fluid). Read more
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